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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4135e5a6a688ecf95fec805acbb3449481e1b1deeb23de752f0bd1e8a0cd9365' 
  AND token = '5DgpYVdw8G7MnsaSG6KMUpNURvDxTIW+95lWU/HM5Tw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}