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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c10c52e0e5fd0caad3cc43007642699fa4c4ef2dff8f6e392155b85aac4de27a' 
  AND token = 'u/QhJrOsSz+B3Ff4r5t0sVgwVjKCj5OWr0UXFbaeqHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}