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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6a569f53156ba4c339eef59fdf3b500787e26d44d9c1efe6c83e3aedc9d8040' 
  AND token = 'We4YVGS44BJgncmRXa2EL+NtbDE9tOC5IcyuiW2jdJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}