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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40e297c7d223b3110e776832940a1dff1e9c9945ed8880d4701b4b1ab23e84ff' 
  AND token = 'ACQo2j3TQOgfe2EsxrR/3E/4bngEOV0z0le9iJ9h5sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}