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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05fd327e5599b009ba337ec6989058fb27d5d2de0aa9efab430b32b75c9f5098' 
  AND token = 'XOKMrL3SF+SjZCXf1dVR0jN9Re6z4j3T6IAXkxO6iT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}