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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ac6c45d8e4647797e4e1a21d17fcec9f26a331144c074a33948708404dbd0e4' 
  AND token = 'KvL0ySQM1rnvDDiPRa/9Y0kEANiBlWLF05T3JljyOt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}