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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d7542d55c5f03c5801c3ebf380e896f2afed78defc7b4f68c47004304359d1d' 
  AND token = 'RN3nTQ+wQYTFvRni+XQg02G89zo5MGMKEz+9mo34tws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}