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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '404505bf2ea3d076f7bcea330beeed5cc863387b7c04b1274726334114248f80' 
  AND token = 'h5d4EWmV22DKeHc7395MtUktefrV/4zPALgJAqjvy6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}