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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfa08879e0c1f3cb25997ed6b484d33d2b1233a14414953b214c96103103a822' 
  AND token = '4O+AGebnjySCssGaC9Yr2/dvUvLwFXmBhLTa62aXUiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}