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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1e43694f6a71577b75849c5e90935c6e8801a2874c5eb01c6ad2a8138e59731' 
  AND token = 'V0Xeemvq/O8c7ZTuN9D2H89UrY+blzd+Z+zcpoE0/5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}