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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0e8163d9809ec3575a6aa78441415055b8dd41dfa55ac33a96d39e0a7a17d44' 
  AND token = 'Q/4ikeZLgQ+4AvSQsAyU/wpWFTP0lGY8dowrN8adclQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}