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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5caec78763ed5d36881e17a8da49c5a9ea7bfba1284280220956372aa50b78b7' 
  AND token = 'muySno6/QM7yzNO/tIyv98fK7CAiunMrXZ54BsZ6yvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}