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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5073129e3b9d7a53174eb46de98a793f5482da89aa1ee2b57e8f0e32d7d83814' 
  AND token = 'QPUMPdvCGgTvlZrPfAeV0m6HLwBeTyoNLnjvfDNk020=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}