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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c565e4cb565fcfd0bfdd26f7d778ebbf2f16792fd45e333b256fef70d556054' 
  AND token = '4C4QS+t7WmB/XrE4Bf7zeQSHeS7sGQGHt2tdbp6L0VU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}