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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56480a6cfd72737a200aa1d9273a6ba970d9b41d6448a43202938258c0b19b65' 
  AND token = 'Pb4Y2aPWBAGb4d/L9WPL7mR825eMFvyvF3dwnnpywiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}