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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0092b9598f93fcdf7c3006fa9cd66281db3ba4cf3de7b10967a0b9446b83e505' 
  AND token = 'IR1z1Ph1W+HI4tZ8+XFkjup/FTFpaIKkqH6elpM1L0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}