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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5e0f4688a87f53e64eb23fbcdc124d75bb5c79461ffb47d8ca4ea4661a165b6' 
  AND token = 'bLC1YgXYrpwZy16+OIAdSX8YqwO6pE99lLkHwmNLBRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}