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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '531782d2745ee4373c322db26ed258db773461c5ee20d4bd7b95f54b95a4bc66' 
  AND token = '44TCCZ9cZFRPhMHBhYnonXkS9EGhDdkvGNc/6vZPqZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}