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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da9f1ad9dc759c63bd319c4f1e1209c458cb98860d799b50e40f9ba16e697a50' 
  AND token = 'tqdpMuLuuPvSWPUGlq3pBPywkWM1Oh5F3uglPggTWuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}