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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1850effc4d567e68378fc217b39cc0db74423a8dacadd3ab6ce05744d1fd7ae3' 
  AND token = 'ZYnFv2yD1C7TnbhPsqNfXOJOePC98GyTROJa0dl6cWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}