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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82712d1039b9f4f058256f683d7b7d8880711ec215f3cab764bce861ef4e8e48' 
  AND token = 'a4f3XtTzseeiwuBuGUOVLeYSJikm1UOA0B5tsgs3wr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}