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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe4e301b48f95dd5e5b6a13ccfae5f8e484a6a91dcab342b3d213e19adf0414d' 
  AND token = 'JDMut2tqmHXBDE3BuKKP3EMBrcfwpQKZPbh1nEZR4/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}