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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac5e02233cb7ec0e8146014347411938a6ea233c4c56e2a8b023a088e9dd30a2' 
  AND token = 'NI9MIoiUYRkeeDqXflS0zpsM2bChpN8A+5TqO5xYoJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}