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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e66667f0b89f9d7376706b27a7a2c29875a21f4b61462dab11c2b4ac6940523' 
  AND token = '/Vv52qQEUN3Ps9CVe6C+Yl6+W3/L9dMdOFvscAY/dzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}