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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3de5bff2b92071383f5a5e28f4f5925131b2620587b9b1ac3b9e601eb9b35391' 
  AND token = 'imvS8y2b+Xcfhjv+9HubmlXKICTF49WzNcAWnQJGNV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}