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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '648cb5f2b578bb9c683723202761ff05ae09810e91d4bb9a1a67e4d58ac2418e' 
  AND token = 'IRv6OLsMiRbMFQdgGR4h4rfjp8Ro5LSuQVlK6IjMZlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}