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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f28c94c3d9e8c27a28a21014c4058eb68d816137c17f29b4a79a977821d0268' 
  AND token = '07HQRpsUr/liMIsKYCRdTt75XU0r117NggcfXDOrtI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}