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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6d8c23e03a1617060bb3c88f80c302e3a4663e657e8b57001372fbc3bc7861d' 
  AND token = 'C3vwVJMT7Wj52GcUFG1+g67EVn+D1hZlJdrbo6/QjvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}