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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e1f9e75f5d6c86856f498434e25fa49656d8a72e8e65d1086cb5fd8051ab9e9' 
  AND token = 'newJCkB5ApbCv0JwnhifoSrDy9kAMzLFNapZd9uMTUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}