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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86c2d0085caab661f07d42bda8d6b3bd64c6765919a9bde1d413f522f9c596fd' 
  AND token = '8PxNTYYuQ84v3PUtad9/+YN9vs1K2jd+l2O8Qd/NGjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}