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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f73f3071f783435f3b0e41e0adf27c69e56e07c4bdbab4f442ff0327a368742' 
  AND token = 'kAIyeGoemzUQAMmoYi/YEk27cKPQKyNvgSi5i3FycNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}