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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b851aee42c9a0d274ed778b884a3098712abee5d9613dc18c530a9cb392af60' 
  AND token = 'HIqR/bJtQZ4o6Ht3NP5Nx33kWScgr2vAJEe9gqzlUPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}