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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd373a50cb7062487aabaadc89f1f89b9a694507398054c7611c116e5e807c091' 
  AND token = '3EbKDjXU9eO2ewI2B2fk4hjmCNbMPjl3NSuCNzp0k2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}