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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d71257f3ce82703ce340fd3e91adef3d120c80f2001ea023de08be2dfd1c648' 
  AND token = '9xE7cuBuM2BNjd6RQ85TwrL+PY5KZVsG4SD9wCtaZJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}