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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e3e2e6d6094414c2c344ab1d0730b090429cdcbd49398a5c6e1a3b14e34caed' 
  AND token = 'cuHu/usctWMupP3+Rlzum5I9GY6HF1SUoV2/Cspo/p8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}