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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b217b279eb8c5422aaf5142248f84cf8e9ae1082e15a6efefcfcff656d500074' 
  AND token = 'sRMiIUUqd9xHNEgl+oaCwsE0GijslPvvH0Z5m61C75A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}