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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d6d0fbc252dc96d0a20e21524cf803f2a94b976967cde3405fee72b9612e2c0' 
  AND token = 's5v/RngMNHKeySb+df/danXTPPJJAiKTnEg4mXFEh1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}