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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43e83c9ff7eb2295770b563c1bcdcc060c80374fc78023678a931fe1bf00d0a1' 
  AND token = 'tidUCcC0UKNrxGfSP3MIttHr4wehhnegPizVg6zy3QQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}