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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '993276b6d82c46e35a34c3c714109449c942bb6fbe60cc2a904440c57e1aedc5' 
  AND token = 'ouNZy0UmAUcItYedm/sFs6gDzT+DFbWgpUD6YqJkbDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}