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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5245c20a3e96e408465ac6b373014f024d0fefae1fc084fc2cc9727e58bbcb8e' 
  AND token = 'eUDB33TUWZNbJQ9MRWBzNfbLQ5Oe7uCR2fTvnL2o1bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}