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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50f543c932ae9b2905a5bde46170d99fb7e9e82c802695462527d3545004162e' 
  AND token = 'ua6sdvYM+Vq4Y4mPripEr07+ODx+PbeoFpaYRK93z50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}