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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c000f578cfebd5f846e77a2f5133590459a6b29f469f0d45c119d301dca0bc1' 
  AND token = 'v+RqsiwCeGB8woqgocix8oh/9R6u9kI7tDiRwNqgOCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}