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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d9eea456c1647e6df1d53cb31ced29ee85c3d3fcf2906dd602e9e07c6b57713' 
  AND token = '0phcVWH/A0TemIId1IyfJn+dXcqhECQUjSwD07Vc8lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}