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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b7743a2e3c9cbb47d074e93309316a8baf5c3ed94abf3fbf002cae577630842' 
  AND token = 'FYbmlzBqEBp5IkCsuRzZH1wtARTO12MPDv3ztqmxYb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}