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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a9627529b04075114a0d7ececeb32cfc0abf3cf53e859d5ebc1027f828f4d4' 
  AND token = 'QDhd4crerKsRa6+K+LNprJZmjhjZB07vAKIwFQebe1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}