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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7212181975dcf0529f8df8a8250ac3fce6a01e9baadda2056962432fc0b67fa8' 
  AND token = 'rPj1gNg8YOeYRRq7cNQdVqHJmaIzeBSAlVhjBcjzvbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}