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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e50f0b7327a551edb6f2d475b1e80b90dd9eade2275716e107441135b08744fe' 
  AND token = 'Jl6ZZC7Ehg4dhG7OCbuZz9DOmIQ8bdS8Z/UWGgSbli8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}