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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69d52166c11c04ce51647c7f6fb7a901e36571ea3a50c37affed595c21892912' 
  AND token = 'n37s9darbyPuCVYFKw2ZQgxnUZn8EAKo8HVNoPy1xK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}