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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '727d84015f30f5d83fec893080cb23f0dac37b26029c9fdbb0b8150b4de61594' 
  AND token = 'E2q3IBRvncB7tgiNBXAmHhcnR0d6hMQl5c8c2lEpxvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}