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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b97e51bf1c413f029e047bf3068405022731c378c1ebd86fd50beaf00e8344d' 
  AND token = '22ShiSwtQ2n0pKQwt2zZ+Hh44S58/MALAxk0JzqAlgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}